Question: I recently read an article on Sculptra that said it was made from polylactic acid and not hyaluronic acid. What is that and how does it differ from the ingredients of other injectable fillers?
Answer: Polylactic acid (PLA) is a filler that is used for facial lipoatrophy. The fillers are commonly called Sculptra. It contains particles of PLA. This is a member of the alpha hydroxyl acid family and is a synthetic polymer. It is also suspended in sodium carboxymethyl cellulose and mannitol. One of the features of Sculptra is it creates stimulation of the native tissue in the body in creating collagen. This helps the result to be more long lasting. However, PLA is metabolized by the body. This differs from the hyaluronic acid filler which is made from a compound that is quite often found normally in the bodies and has been reformulated for surgical use.