Question: I have proven to be allergic to several medications in the past that were animal derived. Will the proteins in Restylane cause allergic reaction at the injection site?
Answer: That’s a good question. Restylane is a hyaluronic acid filler and it is a non-animal source which is good. In general, it can be used well without high risk of an allergic reaction since there are no animal proteins to react to. Some people refer to granulomas after Restylane as an allergic reaction, but they are really just the tissues scarring around the area or maybe just a small blood vessel due to injection. This can be improved with a hyaluronidase injection to the area. If it is due to some bleeding and calcification, this may need to be dealt with in a different way. The good news for Restylane is that since it is not animal derived, there is less chance of having a reaction based on the ingredients.